Krebs Cycle

Krebs cycle is a series of interrelated biochemical reactions occurring in all living cells, which takes place in the inner membrane of mitochondria. 

This involves a metabolic patyway during which pyruvate is broken down into carbon dioxide and water to generate energy. 

Krebs cycle also called citric acid cycle or tricarboxylic acid (TCA) cycle.

Link Reaction

Pyruvates enter mitochondria and initiates the link reaction between glycolysis and Krebs cycle by forming acetyl CoA.

Krebs Cycle

Acetyl CoA initiates the Krebs cycle by combining with oxaloacetate(4C) to form citrate. Citrate is decarboxylated and dehydrogenated through a series of reactions.

Energy is stored in the form of NADH, FADH2 AND GTP.

Two molecule of carbon dioxide are released as waste product during Krebs cycle.

NAD and FAD are hydrogen acceptors.

One molecule of ATP is gained at the end of the cycle.

Krebs cycle provides hydrogen for use in ETC to provide energy for the formation of ATP.